An Atlas of Immune Cell Exhaustion in HIV-Infected Individuals Revealed by Single-Cell Transcriptomics.
The effects of HIV infection on immune cell exhaustion at the transcriptomic level was investigated by analyzing single-cell RNA sequencing of peripheral blood mononuclear cells from four healthy subjects (37,847 cells) and six HIV-infected donors (28,610 cells).
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Atlas
Analysis Portals
NoneProject Label
ImmuneCellExhaustianHIVSpecies
Homo sapiens
Sample Type
specimens
Anatomical Entity
blood
Organ Part
Unspecified
Selected Cell Types
Unspecified
Disease Status (Specimen)
HIV infectious disease
Disease Status (Donor)
HIV infectious disease
Development Stage
human adult stage
Library Construction Method
10X 3' v2 sequencing
Nucleic Acid Source
single cell
Paired End
falseAnalysis Protocol
optimus_post_processing_v1.0.0, optimus_v4.2.3File Format
Cell Count Estimate
43.7kDonor Count
4