HCA Data Explorer

Construction of A Human Cell Landscape by Single-cell mRNA-seq

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Updated April 13, 2023

Single-cell RNA sequencing was used to determine the cell type composition of all major human organs and construct a basic scheme for the human cell landscape (HCL).

Xiaoping HanCenter for Stem Cell and Regenerative Medicine, Zhejiang University School of Medicinexhan@zju.edu.cn
Guoji GuoCenter for Stem Cell and Regenerative Medicine, Zhejiang University School of Medicineggj@zju.edu.cn
Xiaoping Han1
Guoji Guo1
Ziming Zhou1
Lijiang Fei1
Huiyu Sun1
Renying Wang1
Yao Chen2
Haide Chen1
Jingjing Wang1
Huanna Tang3
Wenhao Ge4
Yincong Zhou5
Fang Ye1
Mengmeng Jiang1
Junqing Wu1
Yanyu Xiao1
Xiaoning Jia6
Tingyue Zhang1
Xiaojie Ma7
Qi Zhang8
Xueli Bai8
Shujing Lai1
Chengxuan Yu1
Lijun Zhu4
Rui Lin9
Yuchi Gao10
Min Wang11
Yiqing Wu12
Jianming Zhang13
Renya Zhan14
Saiyong Zhu7
Hailan Hu6
Changchun Wang15
Ming Chen5
He Huang16
Tingbo Liang8
Jianghua Chen3
Weilin Wang4
Dan Zhang12
1Center for Stem Cell and Regenerative Medicine, Zhejiang University School of Medicine
2Department of Reproductive Endocrinology, Women's Hospital, Zhejiang University School of Medicine.
3Kidney Disease Center, The First Affiliated Hospital, Zhejiang University School of Medicine
4Department of Hepatobiliary and Pancreatic Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine
5College of Life Sciences, Zhejiang University
6Center for Neuroscience, Zhejiang University School of Medicine
7Life Sciences Institute, Zhejiang University
8Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine
9Hangzhou Repugene Technology
10Annoroad Gene Technology
11Veritas Genetics Asia
12Department of Reproductive Endocrinology, Women's Hospital, Zhejiang University School of Medicine
13Department of Neurosurgery, The Second Affiliated Hospital, Zhejiang University School of Medicine
14Department of Neurosurgery, The First Affiliated Hospital, Zhejiang University School of Medicine
15Institute of Cancer Research and Basic Medical Sciences of Chinese Academy of Sciences, Cancer Hospital of University of Chinese Academy of Sciences, Zhejiang Cancer Hospital
16Bone Marrow Transplantation Center, The First Affiliated Hospital, Zhejiang University School of Medicine
Ami Day

To reference this project, please use the following link:

https://explore.data.humancellatlas.org/projects/1fac187b-1c3f-41c4-b6b6-6a9a8c0489d1

Supplementary links are provided by contributors and represent items such as additional data which can’t be hosted here; code that was used to analyze this data; or tools and visualizations associated with this specific dataset.

1.https://db.cngb.org/search/project/CNP0000325/
INSDC Project Accessions:
SRP214806
GEO Series Accessions:
GSE134355
INSDC Study Accessions:
PRJNA554845

Downloaded and exported data is governed by the HCA Data Release Policy and licensed under the Creative Commons Attribution 4.0 International License (CC BY 4.0). For more information please see our Data Use Agreement.

Atlas

None

Analysis Portals

CZ CELLxGENECZ CELLxGENE
UCSC Cell BrowserUCSC Cell Browser

Project Label

HumanCellLandscape

Species

Homo sapiens

Sample Type

2 sample types

Anatomical Entity

37 anatomical entities

Organ Part

21 organ parts

Selected Cell Types

Unspecified

Model Organ

3 model organs

Disease Status (Specimen)

16 disease statuses

Disease Status (Donor)

20 disease statuses

Development Stage

9 development stages

Library Construction Method

Microwell-Seq

Nucleic Acid Source

single cell

Paired End

false

Analysis Protocol

analysis_protocol_1

File Format

3 file formats

Cell Count Estimate

703.0k

Donor Count

58
fastq.gz254 file(s)tar1 file(s)xlsx1 file(s)