Single-cell ATAC sequencing reveals the mechanism of human breast cancer metastasis

To obtain more information about the lymph node metastasis of breast cancer cells, we selected the matched positive lymph nodes (PL), and negative lymph nodes (NL) of the same patient to perform integrated analysis. The PL, NL samples were analysed with single-cell ATAC sequencing. Overall design: Single cell ATACseq was performed using the 10X Genomics platform per the manufacturers instructions.

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