GM-CSF-producing T helper cells: a distinct subset of T helper cells.
Single-cell RNA sequencing of memory T cells (CD45RA-CD4+) isolated from the peripheral blood (PBMCs) of 5 healthy human donors. Memory T cells were activated/stimulated with PMA/Ion/GP. A population of GM-CSF-producing Th cells (ThGM) was identified that lacked expression of signature transcription factors and cytokines of established Th lineages.
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Atlas
Analysis Portals
NoneProject Label
TCellsNeuroinflammationSpecies
Homo sapiens
Sample Type
specimens
Anatomical Entity
blood
Organ Part
Unspecified
Selected Cell Types
memory T cell
Disease Status (Specimen)
normal
Disease Status (Donor)
normal
Development Stage
human adult stage
Library Construction Method
10x 3' v3 sequencing
Nucleic Acid Source
single cell
Paired End
falseAnalysis Protocol
optimus_post_processing_v1.0.0, optimus_v4.2.3File Format
Cell Count Estimate
70.0kDonor Count
5