A survey of human brain transcriptome diversity at the single cell level
We used single cell RNA sequencing on 466 cells to capture the cellular complexity of the adult and fetal human brain at a whole transcriptome level. Healthy adult temporal lobe tissue was obtained from epileptic patients during temporal lobectomy for medically refractory seizures. We were able to classify individual cells into all of the major neuronal, glial, and vascular cell types in the brain.
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Atlas
Analysis Portals
Project Label
SurveyhumanBrainTranscriptomediversitySpecies
Homo sapiens
Sample Type
specimens
Anatomical Entity
brain
Organ Part
Selected Cell Types
Disease Status (Specimen)
normal
Disease Status (Donor)
normal
Development Stage
Library Construction Method
Fluidigm C1-based library preparation
Nucleic Acid Source
single cell
Paired End
trueFile Format
Cell Count Estimate
466Donor Count
12