A single cell atlas of the human proximal epididymis reveals cell-type specific functions and distinct roles for CFTR
Spermatozoa released from the testis are unable to fertilize an egg without a coordinated process of maturation in the lumen of the epididymis. Relatively little is known about the molecular events that integrate this critical progression along the male genital ducts in man. Here, single cell RNA-sequencing was used to construct an atlas of the human proximal epididymis.
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Atlas
Analysis Portals
NoneProject Label
ProximalEpididymisCFTRSpecies
Homo sapiens
Sample Type
specimens
Anatomical Entity
testis
Organ Part
epididymis
Selected Cell Types
Unspecified
Disease Status (Specimen)
normal
Disease Status (Donor)
testicular cancer
Development Stage
human adult stage
Library Construction Method
10X 3' v2 sequencing
Nucleic Acid Source
single cell
Paired End
falseAnalysis Protocol
optimus_post_processing_v1.0.0, optimus_v4.2.3File Format
Cell Count Estimate
7.5kDonor Count
3