Single-cell analysis reveals congruence between kidney organoids and human fetal kidney
Human kidney organoids hold promise for studying development, disease modelling and drug screening. However, the utility of stem cell-derived kidney tissues will depend on how faithfully these replicate normal fetal development at the level of cellular identity and complexity. Here, we present an integrated analysis of single cell datasets from human kidney organoids and human fetal kidney to assess similarities and differences between the component cell types.
To reference this project, please use the following link:
Supplementary links are provided by contributors and represent items such as additional data which can’t be hosted here; code that was used to analyze this data; or tools and visualizations associated with this specific dataset.
Downloaded and exported data is governed by the HCA Data Release Policy and licensed under the Creative Commons Attribution 4.0 International License (CC BY 4.0). For more information please see our Data Use Agreement.
Atlas
Analysis Portals
NoneProject Label
SC_analysis_kidney_organoids_fetal_kidneySpecies
Homo sapiens
Sample Type
organoids
Anatomical Entity
skin of body
Organ Part
skin fibroblast
Selected Cell Types
Unspecified
Model Organ
kidney
Disease Status (Specimen)
normal
Disease Status (Donor)
normal
Development Stage
12th week post-fertilization human stage
Library Construction Method
10x 3' V2 sequencing
Nucleic Acid Source
single cell
Paired End
falseAnalysis Protocol
optimus_post_processing_v1.0.0, optimus_v4.2.3File Format
Cell Count Estimate
8.3kDonor Count
1