Assessing Cellular and Transcriptional Diversity of Ileal Mucosa Among Treatment-Naïve and Treated Crohn’s Disease
Crohn’s disease (CD) is a chronic inflammatory disease of the gastrointestinal tract. We used single cell RNA sequencing (scRNAseq) to define the cellular and transcriptional activity of the mucosa at different stages of disease progression in CD. Overall design: Terminal ileal mucosal derived single cells was processed and analyzed using scRNAseq
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Atlas
Analysis Portals
NoneProject Label
diversityOfIlealMucosaSpecies
Homo sapiens
Sample Type
specimens
Anatomical Entity
ileum
Organ Part
ileal mucosa
Selected Cell Types
Unspecified
Disease Status (Specimen)
Disease Status (Donor)
Development Stage
Library Construction Method
10x 5' v1
Nucleic Acid Source
single cell
Paired End
trueAnalysis Protocol
analysis_protocol_1File Format
Cell Count Estimate
139.9kDonor Count
27