HCA Data Explorer

Assessing Cellular and Transcriptional Diversity of Ileal Mucosa Among Treatment-Naïve and Treated Crohn’s Disease

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Updated October 18, 2024

Crohn’s disease (CD) is a chronic inflammatory disease of the gastrointestinal tract. We used single cell RNA sequencing (scRNAseq) to define the cellular and transcriptional activity of the mucosa at different stages of disease progression in CD. Overall design: Terminal ileal mucosal derived single cells was processed and analyzed using scRNAseq

Suresh VenkateswaranEmory Universitysvenk30@emory.edu
Suresh Venkateswaran (Experimental Scientist)1
1Emory University
Bhavik Chand

To reference this project, please use the following link:

https://explore.data.humancellatlas.org/projects/9dd91b6e-7c62-49d3-a3d4-74f603deffdb
None
GEO Series Accessions:INSDC Project Accessions:INSDC Study Accessions:

Atlas

GutGut v1.0

Analysis Portals

None

Project Label

diversityOfIlealMucosa

Species

Homo sapiens

Sample Type

specimens

Anatomical Entity

ileum

Organ Part

ileal mucosa

Selected Cell Types

Unspecified

Disease Status (Specimen)

2 disease statuses

Disease Status (Donor)

2 disease statuses

Development Stage

3 development stages

Library Construction Method

10x 5' v1

Nucleic Acid Source

single cell

Paired End

true

Analysis Protocol

analysis_protocol_1

File Format

4 file formats

Cell Count Estimate

139.9k

Donor Count

27
fastq.gz127 file(s)mtx.gz27 file(s)tsv.gz54 file(s)xlsx1 file(s)