Defining the Activated Fibroblast Population in Lung Fibrosis Using Single Cell Sequencing.
Updated July 19, 2023Single-cell RNA sequencing was applied to identify distinct and dynamic cell populations, including an in-depth analysis of the fibroblast population, in lung fibrosis.
Rebecca Peyser1
Scott MacDonnell1
Yinglin Gao1
Luis Cheng1
Yong Kim1
Theodore Kaplan1
Qin Ruan1
Yi Wei1
Min Ni1
Christina Adler1
Wen Zhang1
Kishor Devalaraja-Narashimha1
Justin Grindley1
Gabor Halasz1
Lori Morton1
1Regeneron Pharmaceuticals, Incorporated
Ami Day
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Analysis Portals
NoneProject Label
Lung_FibroblastsSpecies
Mus musculus
Sample Type
specimens
Anatomical Entity
lung
Organ Part
Unspecified
Selected Cell Types
Unspecified
Disease Status (Specimen)
2 disease statuses
Disease Status (Donor)
2 disease statuses
Development Stage
adult
Library Construction Method
10x 3' v2
Nucleic Acid Source
single cell
Paired End
falseAnalysis Protocol
optimus_post_processing_v1.0.0, optimus_v4.2.2File Format
5 file formats
Cell Count Estimate
18.4kDonor Count
11bam11 file(s)fastq.gz33 file(s)loom12 file(s)tar1 file(s)xlsx1 file(s)