Colonic single epithelial cell census reveals goblet cell drivers of barrier breakdown in inflammatory bowel disease.
Three single cell RNA-sequencing (10x, Chromium) experiments were performed on healthy and inflamed human colonic samples, including from patients with Ulcerative Colitis. The authors characterised the composition of the intestinal epithelial cells in these samples.
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Atlas
Gut v1.0Analysis Portals
NoneProject Label
EpithelialDiversityHealthInflammationSpecies
Homo sapiens
Sample Type
specimens
Anatomical Entity
digestive system
Organ Part
colon
Selected Cell Types
epithelial cell
Disease Status (Specimen)
Disease Status (Donor)
Development Stage
human adult stage
Library Construction Method
10X 3' v2 sequencing
Nucleic Acid Source
single cell
Paired End
falseAnalysis Protocol
4.2.3, optimus_post_processing_v1.0.0File Format
Cell Count Estimate
11.2kDonor Count
6