Single-nucleus RNA sequencing of human cortex affected by multiple sclerosis.
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Updated October 31, 2022Single-nucleus RNA sequencing of human cortex affected by multiple sclerosis cortical lesions.
Arnold R KriegsteinEli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of Californiaarnold.kriegstein@ucsf.edu
David H RowitchEli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of Californiadhr25@medschl.cam.ac.uk
Lucas Schirmer1
Dmitry Velmeshev1
Staffan Holmqvist2
Max Kaufmann3
Sebastian Werneburg4
Diane Jung1
Stephanie Vistnes1
John H Stockley2
Adam Young2
Maike Steindel2
Brian Tung1
Nitasha Goyal1
Aparna Bhaduri1
Simone Mayer1
Jan Broder Engler3
Omer A Bayraktar2
Robin JM Franklin2
Maximilian Haeussler5
Richard Reynolds6
Dorothy P Schafer4
Manuel A Friese3
Lawrence R Shiow1
Arnold R Kriegstein1
David H Rowitch1
1Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California
2University of Cambridge
3Center for Molecular Neurobiology Hamburg, University Medical Center Hamburg-Eppendorf
4University of Massachusetts Medical School
5Genomics Institute, University of California
6Imperial College London
Ami Day
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Atlas
None
Analysis Portals
UCSC Cell Browser
Project Label
MultipleSclerosisLineageDiversitySpecies
Homo sapiens
Sample Type
specimens
Anatomical Entity
brain
Organ Part
3 organ parts
Selected Cell Types
Unspecified
Disease Status (Specimen)
2 disease statuses
Disease Status (Donor)
2 disease statuses
Development Stage
human adult stage
Library Construction Method
10X 3' v2 sequencing
Nucleic Acid Source
single nucleus
Paired End
falseAnalysis Protocol
analysis_protocol, optimus_post_processing_v1.0.0, optimus_v4.2.3File Format
5 file formats
Cell Count Estimate
84.0kDonor Count
21bam21 file(s)fastq.gz42 file(s)loom22 file(s)tar1 file(s)xlsx2 file(s)